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Targeted Disruption of the GRA2 Locus in Toxoplasma gondii Decreases Acute Virulence in Mice

Following invasion into the host cell, the protozoan Toxoplasma gondii secretes a variety of proteins that modify the parasitophorous vacuole. Within the vacuole, the 28-kDa dense granule protein known as GRA2 is specifically targeted to the tubulovesicular network which forms connections with the v...

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Autori principali: Mercier, Corinne, Howe, Daniel K., Mordue, Dana, Lingnau, Maren, Sibley, L. David
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC108503/
https://ncbi.nlm.nih.gov/pubmed/9712765
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