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Targeted Disruption of the GRA2 Locus in Toxoplasma gondii Decreases Acute Virulence in Mice

Following invasion into the host cell, the protozoan Toxoplasma gondii secretes a variety of proteins that modify the parasitophorous vacuole. Within the vacuole, the 28-kDa dense granule protein known as GRA2 is specifically targeted to the tubulovesicular network which forms connections with the v...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Mercier, Corinne, Howe, Daniel K., Mordue, Dana, Lingnau, Maren, Sibley, L. David
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1998
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108503/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9712765/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.9.4176-4182.1998
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