Targeted Disruption of the GRA2 Locus in Toxoplasma gondii Decreases Acute Virulence in Mice

Following invasion into the host cell, the protozoan Toxoplasma gondii secretes a variety of proteins that modify the parasitophorous vacuole. Within the vacuole, the 28-kDa dense granule protein known as GRA2 is specifically targeted to the tubulovesicular network which forms connections with the v...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Mercier, Corinne, Howe, Daniel K., Mordue, Dana, Lingnau, Maren, Sibley, L. David
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Fungal and Parasitic Infections
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108503/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9712765/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.9.4176-4182.1998
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