Binding of the Helicobacter pylori Vacuolating Cytotoxin to Target Cells

The vacuolating cytotoxin of Helicobacter pylori, VacA, enters the cytoplasm of target cells and causes vacuolar degeneration by interfering with late stages of endocytosis. By using indirect immunofluorescence and flow cytometry, we have demonstrated that VacA binds to specific high-affinity cell s...

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Pubblicato in:	Infect Immun
Autori principali:	Massari, Paola, Manetti, Roberto, Burroni, Daniela, Nuti, Sandra, Norais, Nathalie, Rappuoli, Rino, Telford, John L.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Molecular and Cellular Pathogenesis
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108470/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9673292/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.8.3981-3984.1998
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