Binding of the Helicobacter pylori Vacuolating Cytotoxin to Target Cells

The vacuolating cytotoxin of Helicobacter pylori, VacA, enters the cytoplasm of target cells and causes vacuolar degeneration by interfering with late stages of endocytosis. By using indirect immunofluorescence and flow cytometry, we have demonstrated that VacA binds to specific high-affinity cell s...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Infect Immun
Hauptverfasser:	Massari, Paola, Manetti, Roberto, Burroni, Daniela, Nuti, Sandra, Norais, Nathalie, Rappuoli, Rino, Telford, John L.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1998
Schlagworte:	Molecular and Cellular Pathogenesis
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108470/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9673292/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.8.3981-3984.1998
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