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DNA polymerase β is required for efficient DNA strand break repair induced by methyl methanesulfonate but not by hydrogen peroxide

The most frequent DNA lesions in mammalian genomes are removed by the base excision repair (BER) via multiple pathways that involve the replacement of one or more nucleotides at the lesion site. The biological consequences of a BER defect are at present largely unknown. We report here that mouse cel...

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Fortini, Paola, Pascucci, Barbara, Belisario, Federico, Dogliotti, Eugenia
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108440/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10931918/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.16.3040
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