DNA polymerase β is required for efficient DNA strand break repair induced by methyl methanesulfonate but not by hydrogen peroxide

The most frequent DNA lesions in mammalian genomes are removed by the base excision repair (BER) via multiple pathways that involve the replacement of one or more nucleotides at the lesion site. The biological consequences of a BER defect are at present largely unknown. We report here that mouse cel...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Fortini, Paola, Pascucci, Barbara, Belisario, Federico, Dogliotti, Eugenia
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 2000
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108440/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10931918/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.16.3040
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