The Phosphatidylinositol 3-Phosphate Phosphatase Myotubularin- Related Protein 6 (MTMR6) Is a Negative Regulator of the Ca(2+)-Activated K(+) Channel K(Ca)3.1

Myotubularins (MTMs) belong to a large subfamily of phosphatases that dephosphorylate the 3′ position of phosphatidylinositol 3-phosphate [PI(3)P] and PI(3,5)P(2). MTM1 is mutated in X-linked myotubular myopathy, and MTMR2 and MTMR13 are mutated in Charcot-Marie-Tooth syndrome. However, little is kn...

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Autori principali: Srivastava, Shekhar, Li, Zhai, Lin, Lin, Liu, GongXin, Ko, Kyung, Coetzee, William A., Skolnik, Edward Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084293/
https://ncbi.nlm.nih.gov/pubmed/15831468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.9.3630-3638.2005
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