Phosphatidylinositol-3 Phosphatase Myotubularin-Related Protein 6 Negatively Regulates CD4 T Cells

Intracellular Ca(2+) levels rapidly rise following cross-linking of the T-cell receptor (TCR) and function as a critical intracellular second messenger in T-cell activation. It has been relatively under appreciated that K(+) channels play an important role in Ca(2+) influx into T lymphocytes by help...

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Main Authors: Srivastava, Shekhar, Ko, Kyung, Choudhury, Papiya, Li, Zhai, Johnson, Amanda K., Nadkarni, Vivek, Unutmaz, Derya, Coetzee, William A., Skolnik, Edward Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592754/
https://ncbi.nlm.nih.gov/pubmed/16847315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00352-06
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