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Intranuclear degradation of nonsense codon-containing mRNA

Most vertebrate mRNAs with premature termination codons (PTCs) are specifically recognized and degraded by a process referred to as nonsense-mediated mRNA decay (NMD) while still associated with the nucleus. However, it is still a matter of debate whether PTCs can be identified by intranuclear scann...

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Autors principals: Bühler, Marc, Wilkinson, Miles F., Mühlemann, Oliver
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084183/
https://ncbi.nlm.nih.gov/pubmed/12101097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf129
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