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An intragenic methylated region in the imprinted Igf2 gene augments transcription

DNA methylation is usually associated with transcriptional silencing, but in the imprinted mouse Igf2 gene, the paternally expressed copy is methylated in two discrete differentially methylated regions (DMRs). DMR1 is located upstream of the fetal promoters and has been shown to be a methylation sen...

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Bibliografske podrobnosti
Main Authors: Murrell, Adele, Heeson, Sarah, Bowden, Lucy, Constância, Miguel, Dean, Wendy, Kelsey, Gavin, Reik, Wolf
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084166/
https://ncbi.nlm.nih.gov/pubmed/11743023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve248
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