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An intragenic methylated region in the imprinted Igf2 gene augments transcription
DNA methylation is usually associated with transcriptional silencing, but in the imprinted mouse Igf2 gene, the paternally expressed copy is methylated in two discrete differentially methylated regions (DMRs). DMR1 is located upstream of the fetal promoters and has been shown to be a methylation sen...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1084166/ https://ncbi.nlm.nih.gov/pubmed/11743023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve248 |
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