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An intragenic methylated region in the imprinted Igf2 gene augments transcription

DNA methylation is usually associated with transcriptional silencing, but in the imprinted mouse Igf2 gene, the paternally expressed copy is methylated in two discrete differentially methylated regions (DMRs). DMR1 is located upstream of the fetal promoters and has been shown to be a methylation sen...

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Autors principals: Murrell, Adele, Heeson, Sarah, Bowden, Lucy, Constância, Miguel, Dean, Wendy, Kelsey, Gavin, Reik, Wolf
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084166/
https://ncbi.nlm.nih.gov/pubmed/11743023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve248
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