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Initial activation of cyclin-B1–cdc2 kinase requires phosphorylation of cyclin B1
At the G(2)/M transition of the cell cycle, the cdc25c phosphatase dephosphorylates inhibitory residues of cdc2, and cyclin-B–cdc2 kinase (MPF) is activated. Phosphorylation of cyclin B1 induces its nuclear accumulation, and, since cdc25c is also believed to accumulate and activate shortly before G(...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1084145/ https://ncbi.nlm.nih.gov/pubmed/12034754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf111 |
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