Nuclear localization of cyclin B1 mediates its biological activity and is regulated by phosphorylation

M-phase promoting factor or maturation promoting factor, a key regulator of the G(2) → M transition of the cell cycle, is a complex of cdc2 and a B-type cyclin. We have previously shown that Xenopus cyclin B1 has five sites of Ser phosphorylation, four of which map to a recently identified cytoplasm...

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Bibliographic Details
Main Authors: Li, Jianke, Meyer, April N., Donoghue, Daniel J.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences of the USA 1997
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC19542/
https://ncbi.nlm.nih.gov/pubmed/9012813
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