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Requirement of functional telomeres for metaphase chromosome alignments and integrity of meiotic spindles
Telomerase deficiency in the mouse eventually leads to loss of telomeric repeats from chromosome ends and to end-to-end chromosome fusions, which result in defects in highly proliferative tissues. We show that telomere dysfunction resulting from telomerase deficiency leads to disruption of functiona...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2002
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1084019/ https://ncbi.nlm.nih.gov/pubmed/11882542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf055 |
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