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Ran Is Required before Metaphase for Spindle Assembly and Chromosome Alignment and after Metaphase for Chromosome Segregation and Spindle Midbody Organization

The Ran pathway has been shown to have a role in spindle assembly. However, the extent of the role of the Ran pathway in mitosis in vivo is unclear. We report that perturbation of the Ran pathway disrupted multiple steps of mitosis in syncytial Drosophila embryos and uncovered new mitotic processes...

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Detalhes bibliográficos
Main Authors: Silverman-Gavrila, Rosalind V., Wilde, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1415283/
https://ncbi.nlm.nih.gov/pubmed/16481399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-10-0991
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