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Ran Is Required before Metaphase for Spindle Assembly and Chromosome Alignment and after Metaphase for Chromosome Segregation and Spindle Midbody Organization

The Ran pathway has been shown to have a role in spindle assembly. However, the extent of the role of the Ran pathway in mitosis in vivo is unclear. We report that perturbation of the Ran pathway disrupted multiple steps of mitosis in syncytial Drosophila embryos and uncovered new mitotic processes...

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Hlavní autoři: Silverman-Gavrila, Rosalind V., Wilde, Andrew
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1415283/
https://ncbi.nlm.nih.gov/pubmed/16481399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-10-0991
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