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Requirement of functional telomeres for metaphase chromosome alignments and integrity of meiotic spindles

Telomerase deficiency in the mouse eventually leads to loss of telomeric repeats from chromosome ends and to end-to-end chromosome fusions, which result in defects in highly proliferative tissues. We show that telomere dysfunction resulting from telomerase deficiency leads to disruption of functiona...

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Bibliografski detalji
Glavni autori: Liu, Lin, Blasco, Maria A., Keefe, David L.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084019/
https://ncbi.nlm.nih.gov/pubmed/11882542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf055
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