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GAAP-1: a transcriptional activator of p53 and IRF-1 possesses pro-apoptotic activity

The mechanisms that regulate the transcription of the tumour suppressor genes p53 and IRF-1 are poorly understood. We have characterized a 68-kDa transcription factor, GAAP-1 (gatekeeper of apoptosis activating proteins), encoded by an alternative splice product of the PRDII-BF1 gene, that recognize...

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Detalhes bibliográficos
Main Authors: Lallemand, Christophe, Palmieri, Marta, Blanchard, Brigitte, Meritet, Jean-François, Tovey, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083973/
https://ncbi.nlm.nih.gov/pubmed/11818340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf032
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