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Wnt signals are transmitted through N-terminally dephosphorylated β-catenin
β-catenin mediates Wnt signaling by acting as the essential co-activator for TCF transcription factors. Wnt signaling increases the half-life and therefore the absolute level of β-catenin in responding cells. The current model states that these changes in β-catenin stability set the threshold for Wn...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1083921/ https://ncbi.nlm.nih.gov/pubmed/11751573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf002 |
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