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Normal neurogenesis and scrapie pathogenesis in neural grafts lacking the prion protein homologue Doppel

The agent that causes prion diseases is thought to be identical to PrP(Sc), a conformer of the normal prion protein PrP(C). Recently a novel protein, termed Doppel (Dpl), was identified that shares significant biochemical and structural homology with PrP(C). To investigate the function of Dpl in neu...

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Détails bibliographiques
Auteurs principaux: Behrens, Axel, Brandner, Sebastian, Genoud, Nicolas, Aguzzi, Adriano
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083878/
https://ncbi.nlm.nih.gov/pubmed/11306558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve088
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