MCM3AP, a novel acetyltransferase that acetylates replication protein MCM3

The MCM proteins are essential for the initiation of DNA replication. We have isolated an MCM3-associated protein (MCM3AP) in a two-hybrid screen using MCM3. Here we demonstrate that MCM3AP is an acetyltransferase which acetylates MCM3 and that chromatin-bound MCM3 is acetylated in vivo. The MCM3 ac...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Takei, Yoshinori, Swietlik, Magdalena, Tanoue, Akito, Tsujimoto, Gozoh, Kouzarides, Tony, Laskey, Ronald
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2001
Pynciau:
Scientific Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083822/
https://ncbi.nlm.nih.gov/pubmed/11258703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve026
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