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MCM3AP, a novel acetyltransferase that acetylates replication protein MCM3

The MCM proteins are essential for the initiation of DNA replication. We have isolated an MCM3-associated protein (MCM3AP) in a two-hybrid screen using MCM3. Here we demonstrate that MCM3AP is an acetyltransferase which acetylates MCM3 and that chromatin-bound MCM3 is acetylated in vivo. The MCM3 ac...

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Hlavní autoři: Takei, Yoshinori, Swietlik, Magdalena, Tanoue, Akito, Tsujimoto, Gozoh, Kouzarides, Tony, Laskey, Ronald
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083822/
https://ncbi.nlm.nih.gov/pubmed/11258703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve026
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