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Chunnel vision: Export and efflux through bacterial channel-tunnels

The Escherichia coli TolC protein is central to toxin export and drug efflux across the inner and outer cell membranes and the intervening periplasmic space. The crystal structure has revealed that TolC assembles into a remarkable α-helical trans-periplasmic cylinder (tunnel) embedded in the outer m...

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Detalhes bibliográficos
Main Authors: Andersen, Christian, Hughes, Colin, Koronakis, Vassilis
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083749/
https://ncbi.nlm.nih.gov/pubmed/11269495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvd075
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