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DNA conformation driven by AP-1 triggers cell-specific expression via a strong epithelial enhancer

We report here the characterization of the regulatory region of the human LAMA3 gene, coding for the α3A chain of laminin-5. A 202 bp fragment is sufficient to confer epithelial-specific expression to a thymidine kinase promoter through the cooperative effect of three AP-1 binding sites. Remarkably,...

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Detalhes bibliográficos
Main Authors: Virolle, Thierry, Djabari, Zied, Ortonne, Jean-Paul, Aberdam, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083743/
https://ncbi.nlm.nih.gov/pubmed/11269498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvd066
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