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DNA conformation driven by AP-1 triggers cell-specific expression via a strong epithelial enhancer
We report here the characterization of the regulatory region of the human LAMA3 gene, coding for the α3A chain of laminin-5. A 202 bp fragment is sufficient to confer epithelial-specific expression to a thymidine kinase promoter through the cooperative effect of three AP-1 binding sites. Remarkably,...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2000
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1083743/ https://ncbi.nlm.nih.gov/pubmed/11269498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvd066 |
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