Rectal and Intranasal Immunizations with Recombinant Urease Induce Distinct Local and Serum Immune Responses in Mice and Protect against Helicobacter pylori Infection

To determine the optimal inductive sites for immunization against Helicobacter pylori infection, the protective efficacy of recombinant urease (rUre) was assessed for mice given the vaccine by either the oral (p.o.), intranasal (i.n.), or rectal route. When mice were immunized with rUre (25 μg p.o....

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Dades bibliogràfiques

Publicat a:	Infect Immun
Autors principals:	Kleanthous, Harry, Myers, Gwendolyn A., Georgakopoulos, Kathleen M., Tibbitts, Timothy J., Ingrassia, Jennifer W., Gray, Heather L., Ding, Ru, Zhang, Zhen-Zi, Lei, Wende, Nichols, Richard, Lee, Cynthia K., Ermak, Thomas H., Monath, Thomas P.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1998
Matèries:	Microbial Immunity and Vaccines
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108285/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9596763/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.6.2879-2886.1998
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