Rectal and Intranasal Immunizations with Recombinant Urease Induce Distinct Local and Serum Immune Responses in Mice and Protect against Helicobacter pylori Infection

To determine the optimal inductive sites for immunization against Helicobacter pylori infection, the protective efficacy of recombinant urease (rUre) was assessed for mice given the vaccine by either the oral (p.o.), intranasal (i.n.), or rectal route. When mice were immunized with rUre (25 μg p.o....

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Detaylı Bibliyografya
Asıl Yazarlar: Kleanthous, Harry, Myers, Gwendolyn A., Georgakopoulos, Kathleen M., Tibbitts, Timothy J., Ingrassia, Jennifer W., Gray, Heather L., Ding, Ru, Zhang, Zhen-Zi, Lei, Wende, Nichols, Richard, Lee, Cynthia K., Ermak, Thomas H., Monath, Thomas P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 1998
Konular:
Microbial Immunity and Vaccines
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC108285/
https://ncbi.nlm.nih.gov/pubmed/9596763
Etiketler: Etiketle
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