Aged BALB/c Mice as a Model for Increased Severity of Severe Acute Respiratory Syndrome in Elderly Humans

Advanced age has repeatedly been identified as an independent correlate of adverse outcome and a predictor of mortality in cases of severe acute respiratory syndrome (SARS). SARS-associated mortality may exceed 50% for persons aged 60 years or older. Heightened susceptibility of the elderly to sever...

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Autores principales: Roberts, Anjeanette, Paddock, Christopher, Vogel, Leatrice, Butler, Emily, Zaki, Sherif, Subbarao, Kanta
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1082763/
https://ncbi.nlm.nih.gov/pubmed/15827197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.9.5833-5838.2005
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