Prior Infection and Passive Transfer of Neutralizing Antibody Prevent Replication of Severe Acute Respiratory Syndrome Coronavirus in the Respiratory Tract of Mice

Following intranasal administration, the severe acute respiratory syndrome (SARS) coronavirus replicated to high titers in the respiratory tracts of BALB/c mice. Peak replication was seen in the absence of disease on day 1 or 2, depending on the dose administered, and the virus was cleared within a...

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Autors principals: Subbarao, Kanta, McAuliffe, Josephine, Vogel, Leatrice, Fahle, Gary, Fischer, Steven, Tatti, Kathleen, Packard, Michelle, Shieh, Wun-Ju, Zaki, Sherif, Murphy, Brian
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC371090/
https://ncbi.nlm.nih.gov/pubmed/15016880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.7.3572-3577.2004
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