Bivalency Is Required for Anticapsular Monoclonal Antibodies To Optimally Suppress Activation of the Alternative Complement Pathway by the Cryptococcus neoformans Capsule

Encapsulated cells of Cryptococcus neoformans are potent activators of the alternative complement pathway. Previous studies found that monoclonal antibodies (MAbs) specific for the major capsular polysaccharide, termed glucuronoxylomannan (GXM), can markedly suppress the ability of the capsule to ac...

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Argitaratua izan da:	Infect Immun
Egile Nagusiak:	Kozel, Thomas R., MacGill, Randall S., Wall, Kevin K.
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 1998
Gaiak:	Fungal and Parasitic Infections
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108087/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9529080/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.4.1547-1553.1998
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