Bivalency Is Required for Anticapsular Monoclonal Antibodies To Optimally Suppress Activation of the Alternative Complement Pathway by the Cryptococcus neoformans Capsule

Encapsulated cells of Cryptococcus neoformans are potent activators of the alternative complement pathway. Previous studies found that monoclonal antibodies (MAbs) specific for the major capsular polysaccharide, termed glucuronoxylomannan (GXM), can markedly suppress the ability of the capsule to ac...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Kozel, Thomas R., MacGill, Randall S., Wall, Kevin K.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Fungal and Parasitic Infections
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108087/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9529080/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.4.1547-1553.1998
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!