Enhanced Protective Antibody Responses to PspA after Intranasal or Subcutaneous Injections of PspA Genetically Fused to Granulocyte-Macrophage Colony-Stimulating Factor or Interleukin-2

Antibody to pneumococcal surface protein A (PspA) has been shown to be protective for Streptococcus pneumoniae infections in mice. In an attempt to define a model for inducing protective antibody to PspA in the absence of adjuvant, we designed two genetic fusions, PspA–interleukin-2 [IL-2]) and PspA...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wortham, Charles, Grinberg, Luba, Kaslow, David C., Briles, David E., McDaniel, Larry S., Lees, Andrew, Flora, Michael, Snapper, Clifford M., Mond, James J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC108082/
https://ncbi.nlm.nih.gov/pubmed/9529075
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados