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Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress
The replication checkpoint kinase Cds1 preserves genome integrity by stabilizing stalled replication forks. Cds1 targets substrates through its FHA domain. The Cds1 FHA domain interacts with Mus81, a subunit of the Mus81-Eme1 structure-specific endonuclease. We report here that Mus81 and Rhp51 are r...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1080131/ https://ncbi.nlm.nih.gov/pubmed/15805465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1304305 |
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