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A Combinatorial Code for Splicing Silencing: UAGG and GGGG Motifs

Alternative pre-mRNA splicing is widely used to regulate gene expression by tuning the levels of tissue-specific mRNA isoforms. Few regulatory mechanisms are understood at the level of combinatorial control despite numerous sequences, distinct from splice sites, that have been shown to play roles in...

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Autori principali: Han, Kyoungha, Yeo, Gene, An, Ping, Burge, Christopher B, Grabowski, Paula J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1079783/
https://ncbi.nlm.nih.gov/pubmed/15828859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0030158
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