Polymorphism in the Bordetella pertussis Virulence Factors P.69/Pertactin and Pertussis Toxin in The Netherlands: Temporal Trends and Evidence for Vaccine-Driven Evolution

The Bordetella pertussis proteins P.69 (also designated pertactin) and pertussis toxin are important virulence factors and have been shown to confer protective immunity in animals and humans. Both proteins are used in the new generation of acellular pertussis vaccines (ACVs), and it is therefore imp...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Infect Immun
Hauptverfasser:	Mooi, Frits R., van Oirschot, Hans, Heuvelman, Kees, van der Heide, Han G. J., Gaastra, Wim, Willems, Rob J. L.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1998
Schlagworte:	Microbial Immunity and Vaccines
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107955/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9453625/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.2.670-675.1998
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