Polymorphism in the Bordetella pertussis Virulence Factors P.69/Pertactin and Pertussis Toxin in The Netherlands: Temporal Trends and Evidence for Vaccine-Driven Evolution

The Bordetella pertussis proteins P.69 (also designated pertactin) and pertussis toxin are important virulence factors and have been shown to confer protective immunity in animals and humans. Both proteins are used in the new generation of acellular pertussis vaccines (ACVs), and it is therefore imp...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Mooi, Frits R., van Oirschot, Hans, Heuvelman, Kees, van der Heide, Han G. J., Gaastra, Wim, Willems, Rob J. L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Microbial Immunity and Vaccines
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107955/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9453625/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.2.670-675.1998
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