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Towards a Recombinant Vaccine against Diphtheria Toxin

Two recombinant fragments of diphtheria toxin (DT) were fused to an engineered tandem repeat of the immunoglobulin (Ig) binding domain of protein A, called ZZ. These fragments are (i) the receptor binding domain (DTR), which comprises amino acids 382 to 535 of DT, and (ii) a linear peptide (DT(168–2...

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Autores principales: Lobeck, Karin, Drevet, Pascal, Léonetti, Michel, Fromen-Romano, Cécile, Ducancel, Frédéric, Lajeunesse, Evelyne, Lemaire, Caroline, Ménez, André
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC107921/
https://ncbi.nlm.nih.gov/pubmed/9453589
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