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Drug Stimulated DNA Cleavage Mediated by Cauliflower Topoisomerase II

We have investigated cauliflower (Brassica oleracea) topoisomerase II with respect to its interaction with DNA and demonstrate that the enzyme shares the characteristics of topoisomerase II purified from a variety of phylogenetically remote organisms. In the presence of the 2-nitroimidazole Ro 15-02...

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Detalhes bibliográficos
Main Authors: Sørensen, Boe S., Fukata, Hideki, Jensen, Palle S., Andersen, Anni H., Christiansen, Kent, Fukasawa, Hirosuke, Westergaard, Ole
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1077584/
https://ncbi.nlm.nih.gov/pubmed/16668035
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