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Protection of Rhesus Monkeys against Infection with Minimally Pathogenic Simian-Human Immunodeficiency Virus: Correlations with Neutralizing Antibodies and Cytotoxic T Cells

We studied the capacity of active immunization of rhesus monkeys with HIV-1 envelope protein (Env) to induce primary virus cross-reactive neutralizing antibodies to prevent infection following intravenous challenge with simian-human immunodeficiency virus (SHIV). Monkeys were immunized with the huma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Quinnan, Gerald V., Yu, Xiao-Fang, Lewis, Mark G., Zhang, Peng Fei, Sutter, Gerd, Silvera, Peter, Dong, Ming, Choudhary, Anil, Sarkis, Phuong T. N., Bouma, Peter, Zhang, Zhiqiang, Montefiori, David C., VanCott, Thomas C., Broder, Christopher C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1075715/
https://ncbi.nlm.nih.gov/pubmed/15731230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.6.3358-3369.2005
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