Protection of Rhesus Monkeys against Infection with Minimally Pathogenic Simian-Human Immunodeficiency Virus: Correlations with Neutralizing Antibodies and Cytotoxic T Cells

We studied the capacity of active immunization of rhesus monkeys with HIV-1 envelope protein (Env) to induce primary virus cross-reactive neutralizing antibodies to prevent infection following intravenous challenge with simian-human immunodeficiency virus (SHIV). Monkeys were immunized with the huma...

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Detalhes bibliográficos
Main Authors: Quinnan, Gerald V., Yu, Xiao-Fang, Lewis, Mark G., Zhang, Peng Fei, Sutter, Gerd, Silvera, Peter, Dong, Ming, Choudhary, Anil, Sarkis, Phuong T. N., Bouma, Peter, Zhang, Zhiqiang, Montefiori, David C., VanCott, Thomas C., Broder, Christopher C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1075715/
https://ncbi.nlm.nih.gov/pubmed/15731230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.6.3358-3369.2005
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