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L1 retrotransposon-mediated stable gene silencing

RNA interference (RNAi) is widely used for functional studies and has been proposed as a potential therapeutic agent. Current RNAi systems are largely efficient, but have limitations including transient effect, the need for viral handling and potential insertional mutations. Here, we describe a simp...

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Autors principals: Yang, Nuo, Zhang, Lin, Kazazian, Haig H.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1072808/
https://ncbi.nlm.nih.gov/pubmed/15800208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni056
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