Enhanced Secretory Production of a Single-Chain Antibody Fragment from Bacillus subtilis by Coproduction of Molecular Chaperones

Formation of inclusion bodies is a major limiting factor for secretory production of an antidigoxin single-chain antibody (SCA) fragment from Bacillus subtilis. To address this problem, three new strains with enhanced production of molecular chaperones were constructed. WB600BHM constitutively produ...

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Bibliographische Detailangaben
Hauptverfasser: Wu, Sau-Ching, Ye, Ruiqiong, Wu, Xu-Chu, Ng, Shi-Chung, Wong, Sui-Lam
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
Schlagworte:
Genetics and Molecular Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC107245/
https://ncbi.nlm.nih.gov/pubmed/9603868
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