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Identification of Neuronal Enhancers of the Proopiomelanocortin Gene by Transgenic Mouse Analysis and Phylogenetic Footprinting

The proopiomelanocortin (POMC) gene is expressed in the pituitary and arcuate neurons of the hypothalamus. POMC arcuate neurons play a central role in the control of energy homeostasis, and rare loss-of-function mutations in POMC cause obesity. Moreover, POMC is the prime candidate gene within a hig...

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Detaylı Bibliyografya
Asıl Yazarlar: de Souza, Flávio S. J., Santangelo, Andrea M., Bumaschny, Viviana, Avale, María Elena, Smart, James L., Low, Malcolm J., Rubinstein, Marcelo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069613/
https://ncbi.nlm.nih.gov/pubmed/15798195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.8.3076-3086.2005
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