Identification of Neuronal Enhancers of the Proopiomelanocortin Gene by Transgenic Mouse Analysis and Phylogenetic Footprinting

The proopiomelanocortin (POMC) gene is expressed in the pituitary and arcuate neurons of the hypothalamus. POMC arcuate neurons play a central role in the control of energy homeostasis, and rare loss-of-function mutations in POMC cause obesity. Moreover, POMC is the prime candidate gene within a hig...

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Main Authors: de Souza, Flávio S. J., Santangelo, Andrea M., Bumaschny, Viviana, Avale, María Elena, Smart, James L., Low, Malcolm J., Rubinstein, Marcelo
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2005
Ábhair:
Gene Expression
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069613/
https://ncbi.nlm.nih.gov/pubmed/15798195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.8.3076-3086.2005
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