The p53 Tumor Suppressor Protein Represses Human snRNA Gene Transcription by RNA Polymerases II and III Independently of Sequence-Specific DNA Binding

Human U1 and U6 snRNA genes are transcribed by RNA polymerases II and III, respectively. While the p53 tumor suppressor protein is a general repressor of RNA polymerase III transcription, whether p53 regulates snRNA gene transcription by RNA polymerase II is uncertain. The data presented herein indi...

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Main Authors: Gridasova, Anastasia A., Henry, R. William
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069601/
https://ncbi.nlm.nih.gov/pubmed/15798209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.8.3247-3260.2005
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