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RNA polymerase III transcription is repressed in response to the tumour suppressor ARF
The tumour suppressor protein ARF provides a defence mechanism against hyperproliferative stresses that can result from the aberrant activation of oncogenes. Accordingly, ARF is silenced or deleted in many human cancers. Activation of ARF can arrest growth and cell cycle progression, or trigger apop...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Oxford University Press
2007
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1888803/ https://ncbi.nlm.nih.gov/pubmed/17439968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm208 |
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