Human Immunodeficiency Virus (HIV) gp41 Escape Mutants: Cross-Resistance to Peptide Inhibitors of HIV Fusion and Altered Receptor Activation of gp120

Human immunodeficiency virus (HIV) infects cells by fusing with cellular membranes. Fusion occurs when the envelope glycoprotein (Env) undergoes conformational changes while binding to cellular receptors. Fusogenic changes involve assembly of two heptad repeats in the ectodomain of the gp41 transmem...

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Detalhes bibliográficos
Main Authors: Desmezieres, Emmanuel, Gupta, Nidhi, Vassell, Russell, He, Yong, Peden, Keith, Sirota, Lev, Yang, Zhongning, Wingfield, Paul, Weiss, Carol D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069567/
https://ncbi.nlm.nih.gov/pubmed/15795263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.8.4774-4781.2005
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