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Escape Mutations Alter Proteasome Processing of Major Histocompatibility Complex Class I-Restricted Epitopes in Persistent Hepatitis C Virus Infection
Mutations in hepatitis C virus (HCV) genomes facilitate escape from virus-specific CD8(+) T lymphocytes in persistently infected chimpanzees. Our previous studies demonstrated that many of the amino acid substitutions in HCV epitopes prevented T-cell receptor recognition or binding to class I major...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1069526/ https://ncbi.nlm.nih.gov/pubmed/15795272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.8.4870-4876.2005 |
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