The Immunodominant Influenza A Virus M1(58–66) Cytotoxic T Lymphocyte Epitope Exhibits Degenerate Class I Major Histocompatibility Complex Restriction in Humans

Cytotoxic T lymphocytes recognizing conserved peptide epitopes are crucial for protection against influenza A virus (IAV) infection. The CD8 T cell response against the M1(58–66) (GILGFVFTL) matrix protein epitope is immunodominant when restricted by HLA-A*02, a major histocompatibility complex (MHC...

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Detalhes bibliográficos
Main Authors: Choo, Joanna A. L., Liu, Jingxian, Toh, Xinyu, Grotenbreg, Gijsbert M., Ren, Ee Chee
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178881/
https://ncbi.nlm.nih.gov/pubmed/24990997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00855-14
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