Effects of Age and Sex on Single-Dose Pharmacokinetics of Tigecycline in Healthy Subjects

The pharmacokinetics of tigecycline was evaluated in 46 healthy young and elderly men and women. Except for the volumes of distribution at steady state (approximately 350 liters in women versus 500 liters in men), there were no significant differences in tigecycline pharmacokinetic parameters. Based...

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Bibliographic Details
Main Authors: Muralidharan, Gopal, Fruncillo, Richard J., Micalizzi, Marlynne, Raible, Donald G., Troy, Steven M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1068643/
https://ncbi.nlm.nih.gov/pubmed/15793165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.4.1656-1659.2005
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