Food and Sex-Related Impacts on the Pharmacokinetics of a Single-Dose of Ginsenoside Compound K in Healthy Subjects

Background and Objectives: Ginsenoside compound K (CK) is a candidate drug for rheumatoid arthritis therapy. This clinical trial was designed to evaluate the effects of food and sex on the pharmacokinetics of CK and its metabolite 20(S)-protopanaxadiol (PPD). Methods: An open-label, single-center, t...

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Publicado en:Front Pharmacol
Autores principales: Chen, Lulu, Zhou, Luping, Wang, Yaqin, Yang, Guoping, Huang, Jie, Tan, Zhirong, Wang, Yicheng, Zhou, Gan, Liao, Jianwei, Ouyang, Dongsheng
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602130/
https://ncbi.nlm.nih.gov/pubmed/28955238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00636
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